He's against roe vs wade, against sane sex marriage, transgender equality etc.
He's been a supporter of all those things to various degrees at various times, though (remember him hugging the rainbow flag, or bragging about letting Caitlyn Jenner use the women's toilet, etc)- that's a big reason I think so many of the people who voted for him thinking he's going be ramming through some ultra-conservative agenda across the board are in for a rude awakening.
I've gotten very little right in the prediction department with this guy, but I can see him being just as likely to cut deals with Pelosi as with Ryan. As someone said earlier, if you look beyond mere campaign rhetoric, based on how he's lived his life and conducted himself, it's more likely he's a rather typical NY liberal than some born-again ultra conservative.