NorthHawk wrote:Even if it doesn't kill people, it can ruin their lungs and set them up for breathing problems for the rest of their lives. Children included, and that might be a whole other problem for an entire generation if they aren't protected from this virus and people who carry it. I hope they have enough data soon to recommend vaccinating younger people.
RiverDog wrote:That was from one study done in Israel, but it's clear that the vaccines do wane or are less effective against certain variants, and even though as you point out that it's still very effective against serious illness, vaccinated people can still spread it, further justifying the need for a booster or a modified vaccine that targets the Delta variant. It also explains why the FDA has changed course and are now recommending that even vaccinated individuals wear masks in certain situations.
Your concern is well justified. The current guideline is that boosters of Pfizer and Moderna are needed 8 months after the 2nd dose. and for now, they're telling people to stick with the same manufacturer. They haven't come up with a recommendation for the J&J vaccine. My wife got a booster last week.
Since it's unlikely that we'll never reach herd immunity through vaccination, we're going to be playing whack a mole, for years perhaps. The good news is that the Pfizer and Moderna vaccines are more easily tweaked to account for different variants, so it's quite possible that we'll be getting shots every 6-8 months for the foreseeable future.
RiverDog wrote:For the most part, even though they seem to be two steps behind the rest of the world, I agree with how the FDA has approached their approval process. Having the data submitted to an independent review board is a very good system of checks and balances. They learned their lesson from the Anthrax vaccine given to troops during the first Gulf War.
Aseahawkfan wrote:It wasn't a study. It was recorded data. Pure and simple. That data I hope is being well recorded here. How many vaccinated people are getting the virus and what effect is it having on them. Pure numbers, not 20 times or 5 times that. Pure numbers.
Your concern is well justified. The current guideline is that boosters of Pfizer and Moderna are needed 8 months after the 2nd dose. and for now, they're telling people to stick with the same manufacturer. They haven't come up with a recommendation for the J&J vaccine. My wife got a booster last week.
Since it's unlikely that we'll never reach herd immunity through vaccination, we're going to be playing whack a mole, for years perhaps. The good news is that the Pfizer and Moderna vaccines are more easily tweaked to account for different variants, so it's quite possible that we'll be getting shots every 6-8 months for the foreseeable future.
Aseahawkfan wrote:We'll see if mandates hold up for constant vaccination. Previous vaccines have been far more effective in eradication, not getting new shots every 6 to 8 months. I'm not sure the case law supports that.
Aseahawkfan wrote:The Anthrax Vaccine was not mandated or able to be taken by anyone other than military personnel or anyone expecting to come into contact with Anthrax. It had very bad side effects and would never have been approved for mandate.
Not sure how you get these parallels sometimes. The government would not have been able to initiate mandates with the public at all if the Anthrax Vaccine level of side effects occurred with the COVID19 vaccines. We wouldn't even see them in use right now if they had those types of problems.
RiverDog wrote:I'm not trying to draw any parallels between various vaccines. All I am saying is that the FDA was burned by the Anthrax incident and that it has affected their thinking with regards to the current crisis, caused them to be more deliberate.
RiverDog wrote:Previous vaccinations have not been more effective than the current Covid vaccines. Small pox, for example, is believed to have existed before the birth of Christ. It took us decades to eradicate it through the widespread use of vaccines. These Covid vaccines, in particular those of Pfizer and Moderna, are truly revolutionary. The only problem with them is that we can't get enough needles into arms.
Covid is a brand new virus. There's a chance that it could eventually die out, mutate into something less contagious, or it could be something that we'll have to deal with for centuries.
Aseahawkfan wrote:Yes. These vaccines are new. But that is why I think we should start sending vaccines abroad. We need to get more needles in arms in other nations. Eradication requires vaccination on a much wider scale. If Americans don't want, we can send them to some other nations. We need to widen the scale.
Small pox eradication required international support for vaccination worldwide.
RiverDog wrote:We have been shipping the vaccines worldwide. As a matter of fact, we have donated more Covid vaccine than all the other countries in the world combined, which includes China, Russia, the UK, Germany, et al. But it's not enough. As of several weeks ago, we've donated 110 million. It needs to be way more than that if we are to be successful. But the other rich countries need to step up to the plate, too.
If you will recall, I was very critical of the Biden Administration sitting on 40 million doses of the Astra Zeneca vaccine, which not only hasn't been approved in this country, they haven't even applied for approval. If we could ever get past this surge of hospitalizations, I would be for the federal government paying health care providers to go on missions to poorer countries and put on vaccination clinics. It's a worldwide pandemic that knows no borders.
Aseahawkfan wrote:This is why I don't worry about China controlling the world. If they aren't going to step up and do right after they screw up early in this pandemic, then they have no chance of being the replacement for the United States.
With all the people painting the United States as the bad guy within the country with all we do positive for the world, I keep wondering who the good guy is when no one steps up like us to help the world even when an idiot is president.
RiverDog wrote:You're preaching to the choir, bro. We Americans don't get near the credit we deserve, especially when you contrast it with all the grief we have to take being the world's policeman. I personally know several medical workers, my orthopedic surgeon that replaced my knee and an x-ray technician friend of mine to name a couple, that have volunteered to go overseas on good will missions and donate their services to those in need that can't afford it. But that stuff doesn't get international headlines.
RiverDog wrote:You're preaching to the choir, bro. We Americans don't get near the credit we deserve, especially when you contrast it with all the grief we have to take being the world's policeman. I personally know several medical workers, my orthopedic surgeon that replaced my knee and an x-ray technician friend of mine to name a couple, that have volunteered to go overseas on good will missions and donate their services to those in need that can't afford it. But that stuff doesn't get international headlines.
Aseahawkfan wrote:I'm not even talking about outside the country. I'm talking about inside the nation where politicians mostly on the Democratic side pillory America, cops, and keep this racial strife alive to maintain votes. They paint us as bad guys inside our nation and overlook all the good we've done over the years and act like we're like the worst bad guys ever while trying to play up Europe and other nations that do less than us to help the world.
I wonder who in their minds are the good guys.
RiverDog wrote:Back to topic. Johnson & Johnson just announced that studies showed that a booster shot of their vaccine resulted in a 9 fold increase in antibody production:
Johnson & Johnson said on Wednesday that studies show a booster shot of its vaccine provides a "rapid and robust increase" in Covid-19 antibodies when used on people who have already received its first dose.
The interim data showed people who already had been given the J&J vaccine experienced a nine-fold increase in spike-binding antibodies compared with 28 days after the first dose, the drugmaker said in a statement.
https://news.yahoo.com/johnson-johnson- ... 42695.html
RiverDog wrote:Back to topic. Johnson & Johnson just announced that studies showed that a booster shot of their vaccine resulted in a 9 fold increase in antibody production:
Johnson & Johnson said on Wednesday that studies show a booster shot of its vaccine provides a "rapid and robust increase" in Covid-19 antibodies when used on people who have already received its first dose.
The interim data showed people who already had been given the J&J vaccine experienced a nine-fold increase in spike-binding antibodies compared with 28 days after the first dose, the drugmaker said in a statement.
https://news.yahoo.com/johnson-johnson- ... 42695.html
c_hawkbob wrote:Maybe J&J shoulda been a 2 shot vaccination all along.
Aseahawkfan wrote:It (Israeli data on vaccine efficacy) wasn't a study. It was recorded data. Pure and simple. That data I hope is being well recorded here. How many vaccinated people are getting the virus and what effect is it having on them. Pure numbers, not 20 times or 5 times that. Pure numbers.
RiverDog wrote:Here's the problem with the Israeli's "pure numbers":
Late last month, researchers in Israel released some alarming new Covid-19 data. The data showed that many Israelis who had been among the first to receive the vaccine were nonetheless catching the Covid virus. Israelis who had been vaccinated later were not getting infected as often.
The study led to headlines around the world about waning immunity — the idea that vaccines lose their effectiveness over time. In the U.S., the Israeli study accelerated a debate about vaccine booster shots and played a role in the Biden administration’s recent recommendation that all Americans receive a booster shot eight months after their second dose.
But the real story about waning immunity is more complex than the initial headlines suggested. Some scientists believe that the Israeli data was misleading and that U.S. policy on booster shots has gotten ahead of the facts. The evidence for waning immunity is murky, these scientists say, and booster shots may not have a big effect.
At first glance, the Israeli data seems straightforward: People who had been vaccinated in the winter were more likely to contract the virus this summer than people who had been vaccinated in the spring.
Yet it would truly be proof of waning immunity only if the two groups — the winter and spring vaccine recipients — were otherwise similar to each other. If not, the other differences between them might be the real reason for the gap in the Covid rates.
As it turns out, the two groups were different. The first Israelis to have received the vaccine tended to be more affluent and educated. By coincidence, these same groups later were among the first exposed to the Delta variant, perhaps because they were more likely to travel. Their higher infection rate may have stemmed from the new risks they were taking, not any change in their vaccine protection.
Sure enough, other data supports the notion that vaccine immunity is not waning much. The ratio of positive Covid tests among older adults and children, for example, does not seem to be changing, Dowdy notes. If waning immunity were a major problem, we should expect to see a faster rise in Covid cases among older people (who were among the first to receive shots). And even the Israeli analysis showed that the vaccines continued to prevent serious Covid illness at essentially the same rate as before.
Statisticians have a name for this possibility — when topline statistics point to a false conclusion that disappears when you examine subgroups. It’s called Simpson’s Paradox.
https://www.nytimes.com/2021/08/30/brie ... shots.html
So the Devil is in the details. As my prof in my first statistics course said in his initial remarks on the first day of class: There are liars, damn liars, and then there are statisticians"
Aseahawkfan wrote:You posted a competing opinion. It doesn't change the Israeli numbers, not sure why you think it does. Then you post a quote about statistical lies when the article you wrote is about a statistician seeing the base data in a different way using statistics. You never seem to see the problem with your own examples. This Israeli data was pure numbers as in just the numbers prior to manipulation by statisticians unlike your article which was a statistician manipulating the data to make it appear better than it is.
Time will tell who is right. Right now we're in the early stages of breakthrough infections. We'll see what happens as more data comes in.
Aseahawkfan wrote:I am absolutely sure this is something to watch and account for. If the vaccines are being blasted through, we absolutely need to know and fast. I would like the CDC and John Hopkins to set up a different tracker for vaccinated versus unvaccinated hospitalizations and deaths that were just the numbers, not articles based on percentages myself. I hope that happens soon.
Aseahawkfan wrote:I have a buddy who told me when he visited the UW medical center some doctor told him the vaccines don't work against the Delta Variant. I could not find a position paper stating this on the UW medical web site, so I doubt it is true. But he believes it. Someone there must have told him something because he doesn't lie.
Aseahawkfan wrote:It seems to be fairly clear that vaccination is not as effective against the Delta variant, but still far better than being unvaccinated versus the Delta Variant.
RiverDog wrote:We have to keep these vaccine effaces in perspective. Last year at this time, the hope was that we'd get a vaccine with an efficacy of at least 60% effectiveness. The CDC had said that they would approve one that had an efficacy of just 50%. The flu shot is only about 40-60% effective. No one ever dreamed that we'd develop vaccines with 95% efficacy, now we're wringing our hands because they've declined to 75%. From July of 2020:
Fauci said he hopes the vaccine will have an efficacy of at least 60%, meaning on average the vaccine reduces a person’s risk of a Covid-19 infection by 60%. “Obviously, we would like to see it much, much higher. But 60% is the standard that you do for the cutoff. That’s not unusual,” he said
https://www.cnbc.com/2020/07/27/dr-anth ... ccine.html
Hawktawk wrote:Wife and I and kid and his girlfriend are booked at clover island this weekend . I’m wondering if we should cancel
Hawktawk wrote:Wife and I and kid and his girlfriend are booked at clover island this weekend . I’m wondering if we should cancel
Aseahawkfan wrote:I just want to be sure they're holding up. Death rate per day is back to 1300 a day. That's no bueno. I want to make sure my parents and highly vulnerable people are getting clear information.
COVID19 is a terrible way to die. I would prefer my parents and older relatives of which I have many are given accurate info so they can plan accordingly.
Hawktawk wrote:If we had contact tracing and antibody testing we might find delta has already infected most of the population in the states with the overwhelming number of cases asymptomatic . Just a theory based on the similar trajectory elsewhere within delta.
Hawktawk wrote:It’s far from over . There are far more mutated variants popping up. And even with delta the peak is far higher than anything before . Spokane is hammered and I have a lot of friends up there including in the medical field who thought this was a joke for 16 months . It could get even worse . Depressing .
Aseahawkfan wrote:It (Israeli data on vaccine efficacy) wasn't a study. It was recorded data. Pure and simple. That data I hope is being well recorded here. How many vaccinated people are getting the virus and what effect is it having on them. Pure numbers, not 20 times or 5 times that. Pure numbers.
RiverDog wrote:Here's another problem with the Israeli "pure numbers". The Israelis administered exclusively Pfizer's vaccine, of which some data is suggesting is quite a bit less effective against the Delta strain than Moderna. I'm not sure what the percentage of vaccines given by brand is in this country, but I'd guess that Moderna is near 30% of the total, enough to influence the data and make it more of an apples vs. oranges comparison.
It's hard to say how the next few months are going to pan out. Vaccination rates have nudged up slightly and there's some evidence suggesting that the Delta variant has begun to decline. Missouri, one of the first Delta hotspots, has seen a dramatic decrease in case rates recently despite the fact that their vaccination rate is well below the national average. On the other hand, we're getting into the fall, more people will be going back indoors, schools are resuming with in person learning, football stadiums will have fans in them, so who knows.
Aseahawkfan wrote:Don't know why you keep putting "pure numbers" in parentheses other than to be annoying. All pure numbers means is absent statistical manipulation. It was just data. Data is more helpful than statistics if you know how to read data, which I do.
Aseahawkfan wrote:And if you want some statistical information how about the studies indicating that natural immunity is as effective as a vaccine as in getting the virus is equally as effective as taking a vaccine. That would indicate a drop would expected because it will sicken and kill the unvaccinated people who haven't boosted immunity with a vaccine, then drop off. Given how infectious the Delta Variant is, this will occur at a faster rate than the original virus. Now that governments have more information available, they are ready to stay open for the most part and let it do its business. Did you read those studies indicating so? They're all over if you look for them. There was no statistical difference in immunity from getting the virus versus taking a vaccine.
https://www.science.org/news/2021/08/having-sars-cov-2-once-confers-much-greater-immunity-vaccine-vaccination-remains-vital
I've seen multiple studies supporting that natural immunity is as effective as a vaccine.
Aseahawkfan wrote:This pandemic is manageable now. Any further lockdowns would be just overly protective BS unless we get a much more lethal variation.
Hawktawk wrote:Just read where New Zealand had their first Covid death in 6 MONTHS!!! They went into lockdown a couple of weeks ago after discovering ONE case . Australia is locked down a couple of weeks into being unlocked with fines of 3700 and jail for violators . Here in America it’s the wild Wild West . We are wrapping up 3 days at clover inn in Kennewick . At least a third un masked spreadnecks with their chest pumped out . An hour ago myself my wife and her girlfriend were in a very small elevator in our masks and some un masked MF says hi there and squeezes in to ride 2 floors . All
I could do to hold my anger in . I hate these MF . America probably won’t lock down no matter how bad it gets but if they have to it will be on the people who will b#tch the most .
Aseahawkfan wrote:This will be interesting. Even the past vaccine mandates did not allow the president to require private companies to mandate vaccines from what I recall reading. The government could do Federal employees and require them in public agencies like schools, but not sure the law allows the government to require private companies to do so. That might be a new test of the ability of government to mandate vaccines.
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